Recombinant Human Insulin-like Growth Factor-1 LR3

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Download COA Batch 20240101

 

Alternate Names	IGF-1, IGF1, IGFI, Somatomedin A, Somatomedin C.
Characteristics
Species	Human
Expression System	E. coli (Escherichia coli)
Fusion Tag	Tag Free
Molecular Weight	9.1 kDa
Specification
Appearance	White lyophilized powder
Purity	≥90%, by SDS-PAGE
Endotoxin Level	< 5.0 EU/mg
Biological Activity	≥1.0 x 10^6 IU/mg by a cell proliferation assay using Bal B/C 3T3 cell
Formulation	Purified by chromatography from E.coli, then lyophilized with Mannitol.
Size	50 µg, 1 mg, and 10 mg
Handling and Storage
Reconstitution	Recommend to reconstitute at 100-200μg/ml concentration in sterile water. Further dilutions can be made in other aqueous buffer.
Shipping	The product is shipped with blue ice.
Storage & Stability	Stored at temperature -20°C for at least 36 months. Please avoid repeated freeze-thaw cycles.

 

Product Description

Human Insulin-like growth factor-1 (hIGF-1) is a hormone similar in molecular structure to insulin. It primarily functions by binding to its specific receptor, the insulin-like growth factor 1 receptor (IGF1R). IGF-1 is one of the most potent natural activators of the AKT signaling pathway, which stimulates cell growth and proliferation and inhibits cell apoptosis.rhIGF-1 LR3 (rhIGF-1 Long Arg3) is an 83-amino-acid analog of IGF-1. It comprises the complete human IGF-1 sequence with an arginine (Arg) substituted for glutamic acid (Glu) at position 3 (hence R3), plus a 13-amino-acid extension peptide at the N-terminus.

The rhIGF-1 LR3, purified by chromatography from E. coli or CHO cells, then lyophilized with Mannitol, has much higher stability and biological activity. The manufacture capability at hundreds of grams scales can meet your large bioprocessing needs.

 

 

Advantages

Chemically Defined & Animal-Free;
High Batch-to-Batch Consistancy;
Stable Bulk Supply
cGMP Manufactured

 

Application

Cell Culture
IVD Reagent Antigens

 

FOR RESEARCH, LABORATORY AND MANUFACTURE USE ONLY. NOT INTENDED FOR DIRECT USE ON HUMANS.

 

Manufacturer: Wuhan Healthgen (Oryzogen)